Interpreting raised serum ferritin levels.
نویسندگان
چکیده
This series of occasional articles provides an update on the best use of key diagnostic tests in the initial investigation of common or important clinical presentations. The series advisers are Steve Atkin, professor of medicine, Weill Cornell Medical College Qatar; and Eric Kilpatrick, honorary professor, department of clinical biochemistry, Hull Royal Infirmary, Hull York Medical School. To suggest a topic for this series, please email us at [email protected].
منابع مشابه
A child with hyperferritinemia: Case report
Hereditary hyperferritinemia cataract syndrome (HHCS) is a rare condition caused by mutations in the gene coding for the light chain of ferritin; it does not lead to iron overload, but it is associated with the risk of developing a bilateral nuclear cataract also in childhood. On the contrary, a raise of serum ferritin levels is a common finding in pediatrics. We describe here a case of HHCS th...
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In a group of 35 children with sickle cell anaemia serum ferritin concentration ranged from 70 to 2460 microgram/l (mean 367, median 180 microgram/l). This was significantly higher than the ferritin levels (range 8-101, mean 34, median 30 microgram/l) in a group of 63 normal control children of the same age group. 30 (86%) of the sickle cell children showed serum ferritin levels greater than 10...
متن کاملFerritin, finger clubbing, and lung disease.
The serum ferritin concentration has been determined by an immunoradiometric assay in 90 subjects with a variety of pulmonary diseases. No association between ferritin concentrations and finger clubbing has been found in any of the diseases studied. Ferritin levels were significantly raised in the subjects with bronchial carcinoma, but were not useful in monitoring recurrence of the tumour. Pul...
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BACKGROUND Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder caused by the loss of motor neurons. Its etiology remains unknown, but several hypothesis have been raised to explain motor neuron death, including oxidative stress. Dysregulation of cellular iron metabolism can lead to increased oxidative stress, and existing data argue for a role of iron metabolism in ALS pathophys...
متن کاملSalivary and Serum Ferritin Levels: Is There a Correlation?
Background and Aim: Blood samples are used for the diagnosis of many diseases. Serum ferritin level is known to be a marker of anemia and iron overload disorders. However, blood collection is an invasive method. Saliva, as a bio-fluid, contains a va-riety of important components that are successfully used for assessment of body health. The use of saliva samples for ferritin evaluation can be re...
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عنوان ژورنال:
- BMJ
دوره 351 شماره
صفحات -
تاریخ انتشار 2015